Serum amyloid A is accepted as an acute phase reactant which increases during the course of inflammatory conditions like IBD.15 Myeloperoxidase is a structural enzyme found in polymorphonuclear leukocytes and critical in innate immune responses, and it catalyzes the formation of hypochlorous acid which causes tissue damage at the site of inflammation.16 In this study, where experimental models are compared, SAA and MPO levels were used as systemic inflammation markers. This evidence concerns the gene MPO and inflammatory bowel disease.