To investigate the role of the PGF2α/PTGFR axis in proliferative retinopathy, we created EC‐specific PTGFR knockout mice (CKO‐T) by crossing Ptgfr‐floxed mice (Wang et al, 2018) with Tie2‐Cre transgenic mice (Kisanuki et al, 2001; Fig 2A). This evidence concerns the gene PTGFR and retinal disorder.