In the brain (Fig. 5C), two proteins (PSP and OAS1) were concordantly associated with more than two phenotypes: (1) PSP was negatively connected to two general diseases (angina and asthma) and one biological trait (DBP), and (2) OAS1 was negatively related to one biological trait (BMI) and one neurological disease (AD). Here, OAS1 is linked to asthma.