The prenatal mIPC signature, inferred as proliferative in our analyses, is consistently enriched in GBM cells, across all states. The gIPC-O signature preferentially matches to >50% of malignant cells in the GBM NPC1-like state and the gIPC-A signature is prevalent in the GBM AC-like state (Fig. 7f). This evidence concerns the gene NPC1 and glioblastoma.