IFNG and rheumatoid arthritis: While the immunosuppressive effect of IFN‐γ on FLS appeared to be mainly translated on the cell membrane by upregulating several inhibitory molecules on the cell membrane of FLS, we hypothesized that the use of cell membranes derived from FLS stimulate with IFN‐γ plus rapamycin might be an effective treatment strategy be designed for RA based on FLSreg.