As additional controls, we used 2 other non-FSHR-expressing cells, AGS gastric adenocarcinoma (Figure 7, C and D) and WM3743 human melanoma (Figure 7E) cells, and D2AP11-TCE did not induce off-target toxicities in these 2 cells either. The gene discussed is FSHR; the disease is gastric adenocarcinoma.