In accordance with this, our transcriptomic data (metabolomic transcript analysis) demonstrated that the mitochondrial electron transport genes ND2, ND3, and ND4, which encode the enzyme NADH dehydrogenase (ubiquinone), and COX1 and COX2, which encode cytochrome c oxidase, were elevated in the cells from nonconverters at baseline and follow-up compared with those from converters and active TB progressors (Supplemental Figure 19). This evidence concerns the gene MT-ND2 and tuberculosis.