ROR2 is a receptor tyrosine kinase involved in WNT-5a signaling, has been described as a prognostic biomarker as well as a potential therapeutic target in gastrointestinal stromal tumors and leiomyosarcomas [53], and its expression correlates with disease severity in osteosarcoma [54]. The gene discussed is NTRK1; the disease is gastrointestinal stromal tumor.