In human STS, UPS and Myxofibrosarcomas were found to have the highest median macrophage score of all sarcoma types [50], and a high number of CD68+ macrophages are discussed as negative prognostic factors for a series of STS, including Osteosarcoma and Ewing Sarcoma (reviewed in [51]). This evidence concerns the gene CD68 and myxofibrosarcoma.