The top 5 proteins exclusively detected in tumor in ≥ 90% of the cases included CD68 (a macrophage marker), Optineurin (OPTN), Nuclear receptor coactivator 5 (NCOA5), RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1) and Stromal cell derived factor 2 like 1 (SDF2L1). Here, SDF2L1 is linked to neoplasm.