Studies focussing on Gal-3BP in renal pathology are limited, while more is known about its ligand Gal-3.19 To our knowledge, no data is available about its expression and possible role as biomarker in common causes of chronic renal pathology, such as hypertension-related glomerulosclerosis or diabetic nephropathy. The gene discussed is LGALS3; the disease is diabetic kidney disease.