C5AR1 and neoplasm: The Tumor Immune Dysfunction and Exclusion (TIDE) [23] scores were significantly greater in the group with high C5aR1 expression as compared to the group with low C5aR1 expression, which indicates that higher expression of C5aR1 mediates the immune-evasion status of the tumor immune microenvironment (TIME) in GC (Figure 6F).