The CSF: serum ratio of IL-6 levels was sufficiently consistent to act as a potential biomarker of intracranial aneurysms (Kaminska et al., 2021), while increased levels of IL-6 in rat brain parenchyma occurred in parallel with plasma and CSF values and with the severity of traumatic brain injury (Chatzipanteli et al., 2012). The gene discussed is IL6; the disease is Dilatation of the cerebral artery.