AKT1 and major depressive disorder: KEGG enrichment analysis revealed that neuroactive ligand–receptor interaction (hsa04080), cAMP signaling pathway (hsa04024), PI3K-Akt signaling pathway (hsa04151), serotonergic synapse (hsa04726), and dopaminergic synapse (hsa04728) are rich in many targets that may contribute to the treatment of depression with TCEF.