AKT1 and atherosclerosis: The significantly enriched KEGG pathways of 111 putative targets contained lipid and atherosclerosis, non-alcoholic fatty liver disease, AMPK signaling pathway, PI3K-Akt signaling pathway, adipocytokine signaling pathway, etc, demonstrate the effect of LAH against NAFLD was closely related to lipogenesis and promoting anti-oxidation effect (Figure 3C).