TNF and sexually transmitted disease: YQCMD was shown to regulate the content of DA, serotonin, and norepinephrine in the cerebral cortex of VD rats, thereby improving learning and memory ability (Peng et al., 2018); reducing the expression of IL-6, TNF-α, and IL-1β; and inhibiting the inflammatory response in the hippocampus of rats with VD (Li W. et al., 2019).