In addition, TQHXD could also increase the content of choline acetyltransferase (ChAT) and reduce the content of acetylcholinesterase (AChE) in the hippocampus, improve hemorheological indicators, and improve learning and memory ability in VD rats (Ge et al., 2015b; Wang et al., 2015). This evidence concerns the gene ACHE and sexually transmitted disease.