Inhibit the inflammatory response: reduce the expression of IL-1β, TNF-α and IL-1; inhibited the vascular endothelial inflammation and reduce neuronal apoptosis; Reduced the levels of APP, β-APP, and Aβ, inhibited the formation of senile plaques; Improve nerve recovery and growth, and synaptic regeneration and plasticity. The gene discussed is IL1A; the disease is Senile plaques.