CASP1 and Parkinson disease: Such as miR-135b mimics showed a reduction in the detrimental consequences of MPP + PD in vitro model (SH-SY5Y and PC-12 PD cells) on pyroptosis, by downregulating the NLR family pyrin domain containing 3 (NLRP3) and Caspase-1 genes (Zeng et al., 2019).