Li et al. suggested that GLIPR1 enhances the proliferation, migration, and invasion of glioblastoma and may be involved in activation of the TIMP1-CD63-ITGB1-AKT signaling pathway, which is a potential target for the clinical prevention or management of glioblastoma (Jiang et al., 2022). This evidence concerns the gene TIMP1 and glioblastoma.