TF and neoplasm: Transferrin expression is much higher in GBM than in other grades of glioma, and 8-hydroxydeoxyguanosine (8-OHd G), which indicates the oxidative stress level, showed the highest expression, thus indicating a positive correlation between the degree of tumor cell malignancy and the occurrence of cellular ferroptosis (Lei et al., 2020; Garcia-Gomez et al., 2022).