Under physiological conditions, the liver mainly synthesizes constituent proteins, such as albumin and transferrin, while in sepsis, the synthesis changes from constituent proteins to acute phase proteins, including procalcitonin, C-reactive protein, complement factor, binding globin α 2-macroglobulin and α 1-acid glycoprotein (Lang et al., 2007; Remick, 2007). Here, CRP is linked to Sepsis.