NUDT1 and pulmonary arterial hypertension: Nudix hydrolase 1 (NUDT1) and PAH-PASMCs hijack persistent oxidative stress and prevent the incorporation of oxidized nucleotides into DNA, thereby allowing cells to escape apoptosis, proliferate and to some extent participate in vascular remodelling in pulmonary hypertension (Mur et al., 2018; Vitry et al., 2021).