In the GSE13507 cohort, we could find that the expression of CDKN2A and MTF1 were significantly higher in BLCA than in normal or surrounding tissues, while DLD, FDX1, GLS, LIAS, and PDHB were lower in BLCA than in normal or surrounding tissues (Figure 2A). The gene discussed is CDKN2A; the disease is bladder transitional cell carcinoma.