Here, we also observed that platelet GSK-3β-total and the ratio of GSK-3β-total to GSK-3β-S9 (rGSK-3β, activity) were significantly increased in T2DM-MCI compared with those of T2DM-nMCI patients, while no difference was observed in GSK-3β-S9 (inactive form, p = 0.484, Figures 6F–H). The gene discussed is GSK3B; the disease is type 2 diabetes mellitus.