SLC16A1 and neoplasm: In addition, high expression of MCT1, MCT2, MCT4 or CD147 is associated with advanced tumor nodal metastasis (TNM) stage and tumor prognosis, and is a marker of poor tumor prognosis (Pertega-Gomes et al., 2011; Pinheiro et al., 2016; Payen et al., 2020).