SLC16A3 and neoplasm: Current studies have shown that MCT1, MCT2 or MCT4 are widely expressed in tumor cell lines and patients with various tumor types, and the expression of MCT subtypes or CD147 is significantly increased in most tumor cells compared with the adjacent normal epithelium (Choi et al., 2014; Pinheiro et al., 2014; De Oliveira et al., 2012).