CDK5RAP2 and microcephaly: Among the genes known to be associated with microcephaly, CDK5 regulatory subunit-associated protein 2 (CDK5RAP2) regulates the replication process of centrosome proteins, and loss or mutation of CDK5RAP2 can cause microcephaly disease (Hassan et al., 2007; Abdullah et al., 2017; Sukumaran et al., 2017).