GO and KEGG enrichment analyses revealed that these ferroptosis-related DEGs were mainly enriched in the apoptotic signaling pathway, reactive oxygen species metabolic process, response to oxidative stress, ferroptosis, p53 signaling pathway, and lipid and atherosclerosis terms, which have been reported to be associated with DR pathogenesis (8, 34–37). Here, TP53 is linked to atherosclerosis.