In the comparison of women with benign tumors, the malignant group had higher post-menopausal status (p 0.0001), higher HE4 level (p 0.0001), higher CA125 value (p 0.0001), elevated ROMA index (p 0.0001), shorter course of disease (p 0.0001), more BMI ≥26 (p 0.0001), higher PG-SGA (p = 0.0002), and higher cachexia rate (p = 0.0002). The gene discussed is WFDC2; the disease is Cachexia.