HMGB2 and cerebral malaria: Studies in rodent malaria parasite P. yoelii have demonstrated a role for HMGB2 in mosquito infection (Gissot et al., 2008) while in P. berghei it acts as an alarmin contributing to the cerebral malaria (Briquet et al., 2015) and confers long-lasting protection in a murine experimental cerebral malaria (Briquet et al., 2020).