The levels of serum IL-2 (4.22 ± 0.468 vs. 9.62 ± 1.04 vs. 14.08 ± 1.665, P <0.001) (Figure 4B) and IL-6 (32.69 ± 1.102 vs. 40.67 ± 1.433 vs. 50.24 ± 2.632, P <0.001) (Figure 4C), as compared with the HC group, were significantly higher in the SLE-nd group but lower in the SLE-nd group than in the SLE-d group. The gene discussed is IL2; the disease is systemic lupus erythematosus.