Among them, suicide rates of HER2 and TNBC survivors were significantly higher than Luminal A and B breast cancer survivors; the suicide risk for HER2 and TNBC subtypes was significantly higher than Luminal A and B. The higher suicide rate and risk for these two subtypes may be due to the malignancy degree and insensitive to adjuvant therapy. The gene discussed is ERBB2; the disease is breast cancer.