KEGG pathway analysis revealed that DEGs were significantly enriched in PI3K-Akt signaling pathway, Proteoglycans in cancer, ECM-receptor interaction, AGE-RAGE signaling pathway, Transcriptional misregulation in cancer, TGF-beta signaling pathway, Bladder cancer, IL-17 signaling pathway (Figures 5C, D). The gene discussed is AKT1; the disease is cancer.