The onset of hepatobiliary disorders, mainly hypertransaminasemia, was detected for ALKi CER (n = 31; 59.6%), ALEC (n = 57; 40.7%), and CRIZ (n = 98; 35.8%), but also for NTB (n = 12; 32.4%) and GEF (n = 111; 30.3%). The gene discussed is CBLN1; the disease is hepatobiliary disorder.