The most common laboratory-related AE of all grades was decreased albumin (53.8%) followed by thrombocytopenia (41.0%), increased aspartate aminotransferase (30.8%), increased γ-glutamyltranspeptidase (25.6%), increased alanine aminotransferase (23.1%), neutropenia (23.1%), and hyperbilirubinemia (20.5%). This evidence concerns the gene ALB and neutropenia.