PSMD2 and bladder transitional cell carcinoma: Firstly, the TCGA-BLCA cohort (P=0.032) and GSE13507 dataset (P=0.005) both showed that BCa patients with higher expression level of PSMD2 showed more worse 5-year survial compared with patients with lower PSMD2 expression (Figures 2A, B), these were consistent with the Kaplan–Meier plotter database (P=0.0021; Figure 2C).