In particular, due to its ability to selectively invade tumor cells, the therapeutic efficacy of a novel genetically engineered VACV carrying the human sodium iodide symporter (hNIS) gene, GLV-1 h153, was investigated in GC along with its potential utility for imaging with (99 m)Tc pertechnetate scintigraphy and 124I positron emission tomography (PET) (110). This evidence concerns the gene SLC5A5 and neoplasm.