In addition, since the upregulation of SLC7A5 is closely related to abnormal amino acid metabolism (9) and immune evasion (37, 38), in this study, we identified the regulatory mechanism of ZNF24 on SLC7A5, which is crucial for the blockade of tumor metabolism and immunotherapy of KRAS mutant LUAD. The gene discussed is ZNF24; the disease is neoplasm.