To further clarify the expression relationship between SLC7A5 and ZNF24 in KRAS mutant lung adenocarcinoma, we selected KRAS mutant lung adenocarcinoma cell lines (A549G12S, H358G12C, and H2122G12C), the KRAS wild-type LUAD cell line CaLu-3 and the lung normal epithelial cell line Beas-2B to detect the expression levels of ZNF24 and SLC7A5. The gene discussed is KRAS; the disease is lung adenocarcinoma.