CD28 and posterior cortical atrophy: Based on immune response score (IRS=0-4, low expression; IRS=4-12, high expression), we found that FCGR3A and HAVCR2 proteins were up-regulated in prostate tissues of PCa patients compared with normal tissues (P<0.01), while the expression of CCR7 and CD28 proteins were not significantly different between them (P>0.05) (Figure 4B).