In addition, proinflammatory substances, such as prostaglandins and cytokines, such as interleukin 1A (IL1A), interleukin 1B (IL1B), and C-X-C motif chemokine ligand 8 (CXCL8), were elevated in cows with preclinical and clinical endometritis [54]. This evidence concerns the gene CXCL8 and endometritis.