Our univariate Cox regression analysis showed that 5 VM-related genes were correlated with the prognosis of patients with GC (Figure 2A), including SERPINF1, TFPI2, CDH5, prostaglandin-endoperoxide synthase 2 (PTGS2) and snail family transcriptional repressor 2 (SNAI2). The gene discussed is TFPI2; the disease is gastric cancer.