TSC22D3 and systemic lupus erythematosus: GILZ mRNA expression was lower in IFN-high SLE patients (n=1317) compared to IFN-low SLE patients (n=439) (0.10 [-0.36 - 0.56] vs 0.26[-0.12 – 0.61], p=0.0003) (Figure 1B), despite higher GC use in the IFN high group (IFN high median [range] prednisolone dose 10 (0–125)mg/day vs IFN low 5 (0–40)mg/day, p<0.001, data not shown).