In univariate analysis, five factors were identified as potential risk factors for post-PCNL SIRS; operation time (p = 0.001), urine culture (p = 0.005), IL-2R (p = 0.001), percentage of CD3+ cells (p = 0.004), WBC count (p = 0.009) (Table 3). The gene discussed is IL2RA; the disease is systemic inflammatory response syndrome.