Thus, unlike type I cells, type II cells can be rescued from CD95-induced apoptosis by inhibiting MOMP (16, 17), for example, GBM overexpress members of the anti-apoptotic Bcl-2 family (18, 19) and downregulate the expression of BAX (20) and pro-apoptotic Bcl-2 proteins. This evidence concerns the gene BCL2 and glioblastoma.