These observations extended to our independent datasets, with negative associations found between FDGScore and CD8 T cells (METABRIC ER-negative: r = -0.42, p < 2.69e-20; GSE65904 (Melanoma): r = -0.34, p = 3.67e-7; GSE119267 (LUAD): r = -0.44, p = 7.02e-09) and Tcm cells (METABRIC ER-negative: r = -0.26, p < 2.58e-8; GSE65904 (Melanoma): r = -0.30, p = 7.17e-6; GSE119267 (LUAD): r = -0.40, p = 2.13e-7) (Supp Figures S5A–C). This evidence concerns the gene CD8A and melanoma.