After 1st infection we observed a 3-4 fold higher frequency of FM+ PCs among all PCs (B220-CD138+TACI+) and about 10-20 times more FM+ PCs in lymph nodes of the experimental group as compared to the saline control group whereas only few FM+ PCs could be found in the bone marrow (BM) (Figures 1C, F, G). Here, SDC1 is linked to infection.