Neutrophil elastase and TNF-α levels were significantly elevated in aneurysm walls covered by thick layers of ILT, while neutrophil gelatinase-associated lipocalin, myeloperoxidase, and neutrophil elastase were positively correlated, and their mediators may infiltrate the thick AAA compartment and weaken the AAA wall (84). This evidence concerns the gene MPO and triple-A syndrome.