Even after adjusting all other potential confounding factors by step (Model 1 to Model 3), there were still positive associations between DAS28-CRP and myopenia in both the patients with early [Model 3, adjusted odds ratio (AOR) 1.558, 95% CI (1.138–2.132), Figure 2A] and established RA [AOR 1.414, 95% CI (1.115–1.792), Figure 2B]. This evidence concerns the gene CRP and rheumatoid arthritis.