APOE and dementia: As shown in Table 2, compared to participants with high vitamin E intake (>23.63 mg/d), the estimated HRs of incident dementia in low intake, low-medium intake, and medium-high intake groups were 2.31 (95% CI 2.20–4.13), 1.80 (95% CI 0.98–3.32), and 1.75 (95% CI 0.95–3.21), respectively, adjusting for age, gender, drinking, smoking, years of education, APOE, physical activity, cognitive activity, BMI, and CESD.