After adjusting for age, hypertension, CHD, lymphocyte count, cardiac troponin I, CK-MB, IL-6, d-dimer, sepsis, and ARDS, the multivariate logistic regression model revealed a considerably higher risk of death than those who did not have a cardiac injury, Moreover, age (OR:1.99, p < 0.001), septicemia (OR:10.39, p < 0.001), and ARDS (OR:6.65, p < 0.0001) were all shown to be independent risk factors for COVID-19 patients' death. This evidence concerns the gene IL6 and Sepsis.