AHR and infection: The human aryl hydrocarbon receptor (AhR) is present in the human gut and interacts with a wide array of microbial metabolites and was shown to detect and react to relative abundances of AHLs, quinolones and phenazines produced by P. aeruginosa to manage immune response over the course of infection (Moura-Alves et al., 2019; Barroso et al., 2021).