CHD3 and disease arising from reactivation of latent virus: As KAP1 binding to the viral genome had been shown to be involved in MIEP repression during latent infection of primary myeloid cells (Rauwel et al., 2015), and because Kap1-associated protein CHD3 is known to bind SERBP1 (Lemos et al., 2003), we assessed the binding of KAP1 to the viral genome in latently infected THP1 cells in the presence or absence of SERBP1.