Further studies will be important to explore the potential benefits of BA in more relevant mouse and/or other animal models of ADPKD (e.g., slower onset disease models, including the hypomorphic Pkd1RC/RC mouse model (Hopp et al., 2012), and in other inducible and Pkd2 mutant animal models). The gene discussed is PKD2; the disease is autosomal dominant polycystic kidney disease.