Endothelium-specific Snail levels, known to drive EndMT, were equally high in 20-week-old and 40-week-old mice two and seven days post injection of 4T1 breast cancer cells (Figure 7C) and VE-CAD levels were lower in the lung homogenates of 40-week-old mice compared to 20-week-old mice two days post injection (Figure 8A). Here, SNAI1 is linked to breast carcinoma.